Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918809 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21605071 | 0.76 | KDM4E (0.47) | RAF1CYP11B1CYP11B2SCN10ALRRK2 | |
| SCHEMBL14007397 | 0.76 | ALDH1A1 (0.44) | RAF1CYP11B1CYP11B2SCN10AJAK2 | |
| Hydrochloric Acid SCHEMBL30147906 | 0.74 | KDM4E (0.45) | RAF1CYP11B1CYP11B2SCN10ALRRK2 | |
| Hydrochloric Acid SCHEMBL21598403 | 0.74 | KDM4E (0.45) | RAF1CYP11B1CYP11B2SCN10ALRRK2 | |
| SCHEMBL28723840 | 0.74 | GPR35 (0.47) | RAF1CYP11B1CYP11B2SCN10ALRRK2 | |
| SCHEMBL936524 | 0.73 | CYP11B1 (0.47) | RAF1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL23928405 | 0.73 | SCN10A (0.43) | CYP11B1CYP11B2SCN10ALRRK2JAK2 | |
| SCHEMBL23562641 | 0.73 | PIK3CB (0.50) | RAF1 | |
| SCHEMBL19775942 | 0.73 | KCNH2 (0.43) | CYP11B1CYP11B2SCN10ALRRK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3447052-B1 | METHODS OF PREPARING NEW IDH1 INHIBITORS | LES LABORATOIRES SERVIER SAS (FR) | 2021-10-20 | — | — | EP | disclosed |