Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 8/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.41 |
| ▸ | SOD3 | P08294 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19032524 | 1.00 | GNAO1 (0.45) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL19032353 | 1.00 | GNAO1 (0.45) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL19032776 | 1.00 | GNAO1 (0.45) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL19040685 | 1.00 | GNAO1 (0.45) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL19040849 | 0.98 | GNAO1 (0.46) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL19032598 | 0.98 | GNAO1 (0.46) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL7994696 | 0.91 | SIGMAR1 (0.49) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL19032635 | 0.91 | SIGMAR1 (0.39) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL29255853 | 0.91 | GNAO1 (0.41) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 | |
| SCHEMBL30596806 | 0.89 | GNAO1 (0.40) | GNAO1GNAI3GNAI1SIGMAR1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896164-A1 | POLYNUCLEOTIDES ENCODING ALPHA-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | ModernaTX, Inc. (US) | 2021-10-20 | — | — | EP | disclosed |