Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 13/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19174208 | 0.83 | MPO (0.63) | MPOSLC6A4 | |
| SCHEMBL6857021 | 0.81 | MPO (0.48) | MPOSLC6A4MEN1KMT2AKDM4E | |
| SCHEMBL17714001 | 0.78 | MPO (0.57) | MPOSLC6A4MEN1KMT2AKDM4E | |
| SCHEMBL20006876 | 0.76 | KCNH2 (0.38) | MPOADRB2 | |
| SCHEMBL19739064 | 0.72 | MEN1 (0.52) | MPOMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4610835 | 0.71 | MEN1 (0.53) | MPOMEN1KMT2AGAA | |
| SCHEMBL18255049 | 0.71 | MPO (0.41) | MPOSLC6A4MEN1KMT2AKDM4E | |
| SCHEMBL8429903 | 0.70 | ALOX15 (0.46) | MPOMEN1KMT2AKDM4E | |
| SCHEMBL16204644 | 0.69 | MEN1 (0.55) | MEN1KMT2AGAA | |
| SCHEMBL20347684 | 0.68 | MEN1 (0.57) | MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299364-B1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2021-10-20 | — | — | EP | disclosed |