Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23940774 | 0.89 | PTPN5 (0.40) | BCL2L1 | |
| SCHEMBL27852489 | 0.78 | BCL2 (0.56) | PTPN1BCL2BCL2L1PTPN2PTPN6 | |
| SCHEMBL25144996 | 0.77 | LDHA (0.41) | PTPN1BCL2BCL2L1PTPN2PTPN6 | |
| SCHEMBL11198850 | 0.76 | SLC5A2 (0.42) | PTPN1BCL2BCL2L1SLC5A2 | |
| SCHEMBL21177982 | 0.73 | PDE4B (0.42) | PTPN1PTPN2PTPN6 | |
| SCHEMBL15313769 | 0.72 | BCL2 (0.41) | PTPN1BCL2BCL2L1PTPN2PTPN6 | |
| SCHEMBL9748771 | 0.71 | PTPN1 (0.51) | PTPN1BCL2BCL2L1 | |
| SCHEMBL23941181 | 0.71 | BCL2 (0.55) | PTPN1BCL2BCL2L1 | |
| SCHEMBL10905236 | 0.70 | PTPN1 (0.53) | PTPN1BCL2BCL2L1PTPN2PTPN6 | |
| SCHEMBL10904856 | 0.70 | PTPN1 (0.53) | PTPN1BCL2BCL2L1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117370-A1 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2023-04-20 | — | — | US | disclosed |
| WO-2021211982-A2 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2021-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117370-A1 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | CYP2B6, TYR, CYP2D6 | PTPN1 3144/4885BCL2 1018/4885BCL2L1 1752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.