Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | HK2 | P52789 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23940774 | 0.80 | PTPN5 (0.40) | PTPN5KDM4ERCE1GABRA1GABRB2 | |
| SCHEMBL28689603 | 0.78 | HDAC4 (0.48) | PDE4BPTPN5GABRA1GABRB2HDAC4 | |
| SCHEMBL9423903 | 0.76 | HDAC4 (0.47) | PDE4BPTPN5KDM4ERCE1GABRA1 | |
| SCHEMBL14781410 | 0.76 | PTPN5 (0.48) | PTPN5GABRA1GABRB2HDAC4HDAC2 | |
| SCHEMBL10770174 | 0.74 | GABRA1 (0.50) | PTPN5KDM4ERCE1GABRA1GABRB2 | |
| SCHEMBL10911038 | 0.74 | GABRA1 (0.61) | PTPN5GABRA1GABRB2HDAC4HDAC2 | |
| SCHEMBL23940765 | 0.74 | ESR1 (0.42) | PTPN5KDM4ERCE1GABRA1GABRB2 | |
| SCHEMBL11022297 | 0.73 | PTPN1 (0.42) | PDE4BPTPN5KDM4EGABRA1GABRB2 | |
| SCHEMBL2870897 | 0.73 | HDAC4 (0.44) | PDE4BPTPN5KDM4EGABRA1GABRB2 | |
| SCHEMBL27747968 | 0.73 | PTGS2 (0.38) | PTPN5GABRA1GABRB2HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142501-A1 | RUBBER COMPOSITION, TIRE, CONVEYOR BELT, RUBBER CRAWLER, VIBRATION-DAMPING DEVICE, SEISMIC ISOLATOR, AND HOSE | 株式会社ブリヂストン | 2019-07-25 | — | — | WO | disclosed |