Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23943567 | 0.86 | MEN1 (0.46) | MEN1KMT2AATMMAPK1CHRM2 | |
| SCHEMBL23943780 | 0.82 | PDE4B (0.52) | MAPK1CHRM2CYP1A2SLC6A4OPRD1 | |
| SCHEMBL4324560 | 0.82 | CYP1A2 (0.57) | MEN1KMT2AMAPK1CHRM2CYP1A2 | |
| SCHEMBL11841171 | 0.82 | CYP1A2 (0.57) | MEN1KMT2AMAPK1CHRM2CYP1A2 | |
| SCHEMBL29756433 | 0.82 | CYP1A2 (0.57) | MEN1KMT2AMAPK1CHRM2CYP1A2 | |
| Hydrochloric Acid SCHEMBL10407517 | 0.80 | APOBEC3A (0.58) | MEN1KMT2AMAPK1CHRM2CYP1A2 | |
| SCHEMBL9397289 | 0.80 | CXCR4 (0.60) | MEN1KMT2ACHRM2CYP1A2SLC6A4 | |
| SCHEMBL18970191 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2ACHRM2CYP1A2SLC6A4 | |
| SCHEMBL23943566 | 0.78 | CYP1A2 (0.47) | MEN1KMT2AATMCHRM2CYP1A2 | |
| SCHEMBL3464158 | 0.78 | MEN1 (0.53) | MEN1KMT2AATMCHRM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |