Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 8/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | CCR2 | P41597 | 1/20 | 0.60 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841171 | 0.94 | CYP1A2 (0.57) | CHRM2MEN1KMT2ACYP1A2SLC6A4 | |
| SCHEMBL29756433 | 0.94 | CYP1A2 (0.57) | CHRM2MEN1KMT2ACYP1A2SLC6A4 | |
| SCHEMBL4324560 | 0.94 | CYP1A2 (0.57) | CHRM2MEN1KMT2ACYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL10407517 | 0.93 | APOBEC3A (0.58) | CXCR4CHRM2MEN1KMT2ACYP1A2 | |
| SCHEMBL16884151 | 0.86 | GAA (0.63) | MEN1KMT2A | |
| SCHEMBL8828170 | 0.86 | SIGMAR1 (0.61) | SLC6A4 | |
| SCHEMBL28191613 | 0.85 | GAA (0.66) | MEN1KMT2A | |
| SCHEMBL23943752 | 0.83 | KMT2A (0.51) | CHRM2MEN1KMT2ACYP1A2SLC6A4 | |
| SCHEMBL1600111 | 0.83 | KMT2A (0.65) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9620928 | 0.83 | KDM4E (0.64) | CXCR4CHRM2MEN1CHRM1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |