Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998623 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL21088489 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL999820 | 0.91 | ALDH1A1 (0.53) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL1000295 | 0.91 | ALDH1A1 (0.61) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL1002568 | 0.91 | ALDH1A1 (0.61) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL999821 | 0.91 | ALDH1A1 (0.53) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL998954 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL998767 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL998765 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HSD17B10EPHX1ADH1BADH1A | |
| SCHEMBL689552 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HSD17B10EPHX1ADH1BADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256489-A1 | METHODS OF TREATING B-CELL MALIGNANCY USING BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2022-12-08 | — | — | WO | disclosed |
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |