SCHEMBL998623

SCHEMBL998623

CC1CCC(NC2CCC(C)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 1/20 0.44
EPHX1 P07099 1/20 0.42
ADH1B P00325 1/20 0.33
ADH1A P07327 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
OPRK1 P41145 1/20 0.31
ADRA2A P08913 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21088489 1.00 ALDH1A1 (0.44) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL23944315 1.00 ALDH1A1 (0.44) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL999820 0.91 ALDH1A1 (0.53) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL1000295 0.91 ALDH1A1 (0.61) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL1002568 0.91 ALDH1A1 (0.61) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL999821 0.91 ALDH1A1 (0.53) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL998954 0.88 ALDH1A1 (0.67) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL998767 0.88 ALDH1A1 (0.67) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL998765 0.88 ALDH1A1 (0.67) ALDH1A1HSD17B10EPHX1ADH1BADH1A
SCHEMBL689552 0.88 ALDH1A1 (0.67) ALDH1A1HSD17B10EPHX1ADH1BADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230231270-A1 Separator and Application Thereof MICROCOSM TECHNOLOGY CO., LTD. (TW) 2023-07-20 US disclosed
US-20230231270-A1 Separator and Application Thereof MICROCOSM TECHNOLOGY CO., LTD. (TW) 2023-07-20 US disclosed
EP-4213290-A2 SEPARATOR AND APPLICATION THEREOF Microcosm Technology Co., Ltd. (TW) 2023-07-19 EP disclosed
WO-2023129464-A1 POLYMER COMPOSITIONS HAVING DENSIFICATION ACCELERATORS AND ROTATIONAL MOLDING PROCESSES FOR MAKING HOLLOW ARTICLES THEREFROM CYTEC INDUSTRIES INC. (US) 2023-07-06 WO disclosed
EP-2864310-B1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECH CORP (US) 2022-10-26 EP disclosed
EP-2545148-B1 TITANIUM AND MOLYBDENUM COMPOUNDS AND COMPLEXES AS ADDITIVES IN LUBRICANTS LUBRIZOL CORP (US) 2019-08-14 EP disclosed
US-9751880-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and imide compound CANON KABUSHIKI KAISHA (JP) 2017-09-05 US disclosed
US-9751880-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and imide compound CANON KABUSHIKI KAISHA (JP) 2017-09-05 US disclosed
US-20160251483-A1 Reactive Functional Siloxane Compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2016-09-01 US disclosed
US-20160115163-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND IMIDE COMPOUND CANON KABUSHIKI KAISHA (JP) 2016-04-28 US disclosed
US-20070054897-A1 1,1-Dicyclohexyl-3-thiazol-2-yl-urea, 3-(5-Chloro-thiazol-2-yl)-1,1-dicyclohexyl-urea, for example; useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial, in particular, type 2 diabetes NOVO NORDISK A/S (DK) 2007-03-08 US disclosed
EP-1723128-A1 HETEROARYL-UREAS AND THEIR USE AS GLUCOKINASE ACTIVATORS NOVO NORDISK A/S (DK) 2006-11-22 EP disclosed
US-20060241300-A1 Phosphazenium salt mixtures containing hexakis(amino)diphosphazenium, tetrakis(amino)-phosphonium and polyaminophosphazenium salts CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2006-10-26 US disclosed
EP-1597220-A2 PHOSPHAZENIUM SALT MIXTURES CONTAINING HEXAKIS(AMINO)DIPHOSPHAZENIUM, TETRAKIS(AMINO)-PHOSPHONIUM AND POLYAMINOPHOSPAZENIUM SALTS Clariant GmbH (DE) 2005-11-23 EP disclosed
WO-2005066145-A1 HETEROARYL-UREAS AND THEIR USE AS GLUCOKINASE ACTIVATORS NOVO NORDISK A/S (DK) 2005-07-21 WO disclosed
WO-2004074296-A2 PHOSPHAZENIUM SALT MIXTURES CONTAINING HEXAKIS(AMINO)DIPHOSPHAZENIUM, TETRAKIS(AMINO)-PHOSPHONIUM AND POLYAMINOPHOSPAZENIUM SALTS CLARIANT GMBH (DE) 2004-09-02 WO disclosed
US-6143917-A FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD UBE INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-0902014-A1 PROCESS FOR PRODUCING ARYL CARBAMATES UBE INDUSTRIES LIMITED (JP) 1999-03-17 EP disclosed
US-4459424-A SECONDARY AMINE, CARBON DISULFIDE, METAL CONTAINING CATALYST AKZONA INCORPORATED (US) 1984-07-10 US disclosed
US-3960886-A Substituted N-arylanilines STERLING DRUG INC. (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241300-A1 Phosphazenium salt mixtures containing hexakis(amino)diphosphazenium, tetrakis(amino)-phosphonium and polyaminophosphazenium salts ANXA3, AP3S1, INPPL1 ALDH1A1 4043/4885HSD17B10 3554/4885EPHX1 2843/4885
US-20160115163-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND IMIDE COMPOUND PPIE, PPIG, PPIA ALDH1A1 742/4885HSD17B10 2264/4885EPHX1 122/4885
US-20070054897-A1 1,1-Dicyclohexyl-3-thiazol-2-yl-urea, 3-(5-Chloro-thiazol-2-yl)-1,1-dicyclohexyl-urea, for example; useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial, in particular, type 2 diabetes GCK, GCKR, HK1 ALDH1A1 520/4885HSD17B10 1182/4885EPHX1 4148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.