SCHEMBL23944662

SCHEMBL23944662

COc1cc2ccccc2cc1-c1c(N)cc(Cl)nc1Br

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 7/20 0.44
HSP90AB1 P08238 7/20 0.44
TLR8 Q9NR97 1/20 0.40
ALDH1A1 P00352 4/20 0.37
HPGD P15428 3/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NQO1 P15559 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DHPS P49366 4/20 0.36
ADRA2B P18089 1/20 0.34
PTGS1 P23219 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 1/20 0.34
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23947504 0.86 HSP90AA1 (0.56) HSP90AA1HSP90AB1ALDH1A1HPGDKDM4E
SCHEMBL23944282 0.81 HSP90AA1 (0.44) HSP90AA1HSP90AB1TLR8ALDH1A1HPGD
SCHEMBL23944917 0.76 ADORA1 (0.41) HSP90AA1HSP90AB1TLR8ALDH1A1HPGD
SCHEMBL23944921 0.74 TLR8 (0.41) HSP90AA1HSP90AB1TLR8ALDH1A1HPGD
SCHEMBL23943886 0.74 TLR8 (0.41) HSP90AA1HSP90AB1TLR8ALDH1A1HPGD
SCHEMBL23944528 0.74 TLR8 (0.38) HSP90AA1HSP90AB1TLR8ALDH1A1HPGD
SCHEMBL23944924 0.71 TLR8 (0.44) HSP90AA1HSP90AB1TLR8ALDH1A1HPGD
SCHEMBL28232454 0.70 NQO1 (0.60) TLR8ALDH1A1HPGDKDM4EMEN1
SCHEMBL22127105 0.70 ALDH1A1 (0.44) HSP90AA1HSP90AB1TLR8ALDH1A1KDM4E
SCHEMBL22534522 0.69 MAPT (0.52) ALDH1A1HPGDKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021210910-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-10-21 WO disclosed