SCHEMBL23944924

SCHEMBL23944924

COc1cc2ccccc2cc1-c1c(Cl)ccnc1N

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.44
HSP90AA1 P07900 4/20 0.40
HSP90AB1 P08238 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
DYRK1A Q13627 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
SLC2A1 P11166 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PDGFRB P09619 1/20 0.39
PDGFRA P16234 1/20 0.39
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
DHPS P49366 2/20 0.37
NQO1 P15559 1/20 0.37
EGFR P00533 1/20 0.36
FGFR1 P11362 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23944921 0.81 TLR8 (0.41) TLR8HSP90AA1HSP90AB1MEN1KMT2A
SCHEMBL25466290 0.76 F12 (0.44) MEN1KMT2ADYRK1AALDH1A1SMN1; SMN2
SCHEMBL23943886 0.75 TLR8 (0.41) TLR8HSP90AA1HSP90AB1MEN1KMT2A
SCHEMBL23944917 0.75 ADORA1 (0.41) TLR8HSP90AA1HSP90AB1MEN1KMT2A
SCHEMBL23944282 0.74 HSP90AA1 (0.44) TLR8HSP90AA1HSP90AB1MEN1KMT2A
SCHEMBL31011660 0.72 PDGFRB (0.41) TLR8HSP90AA1HSP90AB1MEN1KMT2A
SCHEMBL26266194 0.72 ORAI1 (0.47) HSP90AA1HSP90AB1MEN1KMT2AALDH1A1
SCHEMBL23944528 0.72 TLR8 (0.38) TLR8HSP90AA1HSP90AB1MEN1KMT2A
SCHEMBL23944662 0.71 HSP90AA1 (0.44) TLR8HSP90AA1HSP90AB1MEN1KMT2A
SCHEMBL23944686 0.71 HSP90AA1 (0.42) HSP90AA1HSP90AB1EGFRFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402928-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2022-12-22 US disclosed
WO-2021210910-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402928-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CCNL2, CRY1, CRY2 TLR8 4272/4885HSP90AA1 4312/4885HSP90AB1 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.