Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19871863 | 0.86 | CA1 (0.33) | CA1CNR1 | |
| SCHEMBL20118026 | 0.86 | CNR1 (0.38) | ANPEPRNPEPDNPEPALDH1A1CYP1A2 | |
| SCHEMBL23136637 | 0.85 | CA1 (0.32) | CA1 | |
| SCHEMBL24673496 | 0.85 | LMNA (0.36) | CA1LMNA | |
| SCHEMBL24468883 | 0.83 | KDM4C (0.35) | CA1LMNA | |
| SCHEMBL19303231 | 0.83 | EPHX1 (0.38) | CYP2C19CNR1HTT | |
| SCHEMBL22861695 | 0.83 | KDM4C (0.35) | CA1LMNA | |
| SCHEMBL24764060 | 0.83 | KDM4C (0.35) | CA1LMNA | |
| SCHEMBL22509589 | 0.82 | — | — | |
| SCHEMBL19700949 | 0.81 | KDM4C (0.34) | CA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4166136-A1 | INHALABLE PROTEASE INHIBITORS FOR USE IN THE PREVENTION AND/OR TREATMENT OF FIBROTIC AUTOIMMUNE OR INFLAMMATORY LUNG DISEASES | Albert-Ludwigs-Universität Freiburg (DE) | 2023-04-19 | — | — | EP | disclosed |
| WO-2021209620-A1 | CYSTEINE PROTEASE INHIBITORS FOR USE IN THE PREVENTION AND/OR TREATMENT OF CORONAVIRUS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-10-21 | — | — | WO | disclosed |