Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22861695 | 1.00 | KDM4C (0.35) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL24764060 | 1.00 | KDM4C (0.35) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL24673496 | 0.98 | LMNA (0.36) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL27106026 | 0.92 | KDM4C (0.39) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL20016520 | 0.92 | KDM4C (0.39) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL25894503 | 0.92 | KDM4C (0.39) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL19700949 | 0.90 | KDM4C (0.34) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL25123110 | 0.89 | EPHX1 (0.47) | EPHX1CASP2GNAI3GNAO1GNAI1 | |
| SCHEMBL21106776 | 0.89 | EPHX1 (0.47) | EPHX1CASP2GNAI3GNAO1GNAI1 | |
| SCHEMBL17109728 | 0.89 | CASP2 (0.40) | KDM4CKDM4APHF8KDM2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220168430-A1 | THERAPEUTIC METHODS FOR TREATING HEPATITIS B | ARBUTUS BIOPHARMA CORPORATION (US) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168430-A1 | THERAPEUTIC METHODS FOR TREATING HEPATITIS B | HAVCR2, HDGF, FABP1 | KDM4C 3789/4885KDM4A 3669/4885PHF8 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.