Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23695793 | 0.94 | MEN1 (0.63) | MEN1KMT2ACASP2FAAHACHE | |
| SCHEMBL12519763 | 0.92 | MEN1 (0.59) | MEN1KMT2ARECQLTSHRCASP2 | |
| SCHEMBL25831070 | 0.91 | MEN1 (0.52) | MEN1KMT2ARECQLTSHRCASP2 | |
| SCHEMBL14493625 | 0.89 | MEN1 (0.55) | MEN1KMT2ARECQLTSHRCASP2 | |
| SCHEMBL14289047 | 0.89 | MEN1 (0.59) | MEN1KMT2ARECQLTSHREPHX2 | |
| SCHEMBL22026449 | 0.87 | MEN1 (0.53) | MEN1KMT2ARECQLTSHRCASP2 | |
| SCHEMBL13172394 | 0.86 | MEN1 (0.56) | MEN1KMT2ARECQLTSHRCASP2 | |
| SCHEMBL3952391 | 0.85 | ALDH1A1 (0.55) | RECQLTSHRCASP2EPHX2ALDH1A1 | |
| SCHEMBL3953027 | 0.85 | ALDH1A1 (0.55) | RECQLTSHRCASP2EPHX2ALDH1A1 | |
| SCHEMBL12013654 | 0.85 | FAAH (0.64) | TSHRCASP2EPHX2FAAHNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352350-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352350-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | MEN1 4055/4885KMT2A 445/4885RECQL 2866/4885 |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | MEN1 4055/4885KMT2A 445/4885RECQL 2866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.