Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21107628 | 0.89 | PIK3CD (0.35) | ACHEBCHEPIK3CDHRH3 | |
| SCHEMBL23806907 | 0.88 | PIK3CD (0.33) | ACHEBCHEPIK3CD | |
| SCHEMBL22790851 | 0.83 | ACHE (0.37) | ACHEBCHEPIK3CDHRH3 | |
| SCHEMBL22856322 | 0.81 | ACHE (0.33) | ACHEBCHEPIK3CDHRH3 | |
| SCHEMBL23696216 | 0.81 | ACHE (0.33) | ACHEBCHEPIK3CDHRH3 | |
| SCHEMBL24171714 | 0.80 | PIK3CD (0.36) | ACHEPIK3CDHRH3 | |
| SCHEMBL22837640 | 0.76 | HRH3 (0.36) | ACHEBCHEPIK3CDHRH3 | |
| SCHEMBL25691521 | 0.76 | PIK3CD (0.43) | PIK3CDHRH3 | |
| SCHEMBL23695997 | 0.75 | PIK3CD (0.44) | PIK3CDHRH3 | |
| SCHEMBL25108777 | 0.74 | GNAO1 (0.37) | ACHEBCHEPIK3CDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352350-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352350-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | ACHE 2778/4885BCHE 2634/4885PIK3CD 321/4885 |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | ACHE 2778/4885BCHE 2634/4885PIK3CD 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.