Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CDH1 | P12830 | 1/20 | 0.44 |
| ▸ | APC | P25054 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27285560 | 1.00 | KDM4E (0.72) | KDM4EPKML3MBTL1PIK3R1PIK3CA | |
| SCHEMBL19819297 | 0.89 | KDM4E (0.92) | KDM4EPKML3MBTL1LMNAGAA | |
| SCHEMBL19306662 | 0.89 | TDP1 (0.56) | KDM4EPKML3MBTL1PIK3R1PIK3CA | |
| SCHEMBL27734154 | 0.87 | ALDH1A1 (0.66) | KDM4EPKML3MBTL1PIK3R1PIK3CA | |
| SCHEMBL12462566 | 0.87 | ALDH1A1 (0.66) | KDM4EPKML3MBTL1PIK3R1PIK3CA | |
| SCHEMBL21174610 | 0.86 | KDM4E (0.58) | KDM4EPKML3MBTL1PIK3R1PIK3CA | |
| SCHEMBL28110238 | 0.86 | KDM4E (0.72) | KDM4EPKML3MBTL1PIK3R1PIK3CA | |
| SCHEMBL11263581 | 0.86 | KDM4E (0.72) | KDM4EPKML3MBTL1PIK3R1PIK3CA | |
| SCHEMBL1545355 | 0.85 | KDM4E (1.00) | KDM4EPKML3MBTL1LMNAGAA | |
| SCHEMBL1301829 | 0.85 | ALDH1A1 (0.68) | KDM4EPKML3MBTL1PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210328153-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210328153-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | IDO1, IDO2, AZI2 | KDM4E 156/4885PKM 1167/4885L3MBTL1 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.