SCHEMBL23946308

SCHEMBL23946308

Cc1nc(-c2ccccc2)c2c(F)c(F)c(F)c(-c3ccccc3)c2n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
DHODH Q02127 5/20 0.36
NPY5R Q15761 2/20 0.35
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 2/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
NTRK1 P04629 2/20 0.34
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TOP1 P11387 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CHEK1 O14757 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23946305 0.76 KDM4E (0.36) GRM5L3MBTL1PTGS1PTGS2DHODH
SCHEMBL10205902 0.73 L3MBTL1 (0.54) L3MBTL1PTGS1PTGS2TDP1KDM4E
SCHEMBL24394847 0.70 L3MBTL1 (0.42) L3MBTL1DHODHTDP1KDM4EPOLB
SCHEMBL18553158 0.68 DHODH (0.41) L3MBTL1DHODHTDP1KDM4EMAPT
SCHEMBL23009767 0.67 L3MBTL1 (0.56) L3MBTL1PTGS1PTGS2DHODHTDP1
SCHEMBL23946256 0.67 L3MBTL1 (0.39) L3MBTL1PTGS1PTGS2NPY5RTDP1
SCHEMBL7713106 0.66 LMNA (0.48) GRM5DHODHTDP1MAPTALDH1A1
SCHEMBL247368 0.66 LMNA (0.48) GRM5DHODHMAPTALDH1A1
SCHEMBL2725521 0.66 LMNA (0.39) GRM5DHODHKDM4EPOLBMAPT
SCHEMBL28877316 0.66 ADORA2A (0.43) GRM5KDM4EMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES IDO1, IDO2, AZI2 GRM5 659/4885L3MBTL1 2765/4885PTGS1 2472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.