Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.66 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.42 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MDH2 | P40926 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 5/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23947991 | 0.92 | PTPN22 (0.68) | PTPN22F10PRSS1PLAUPLAUR | |
| SCHEMBL23947343 | 0.89 | PTPN22 (0.74) | PTPN22F10PLAUPLAURCTSL | |
| SCHEMBL23947993 | 0.87 | PTPN22 (0.72) | PTPN22F10PLAUPLAURCTSL | |
| SCHEMBL23947371 | 0.86 | PTPN22 (0.75) | PTPN22PLAUPLAURCTSLCTSB | |
| SCHEMBL23948060 | 0.84 | PTPN22 (0.79) | PTPN22PLAUPLAURCTSLCTSB | |
| SCHEMBL23947423 | 0.84 | PTPN22 (0.78) | PTPN22PLAUPLAURCTSLCTSB | |
| SCHEMBL23947992 | 0.83 | PTPN22 (0.77) | PTPN22PLAUPLAURCTSLCTSB | |
| SCHEMBL23947424 | 0.83 | PTPN22 (0.77) | PTPN22PLAUPLAURCTSLCTSB | |
| SCHEMBL23947990 | 0.83 | PTPN22 (0.77) | PTPN22PLAUPLAURCTSLCTSB | |
| SCHEMBL23947934 | 0.83 | PTPN22 (0.71) | PTPN22PLAUPLAURERAP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211191-A1 | NOVEL LYMPHOID-SPECIFIC TYROSINE PHOSPHATASE (LYP) INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2021-10-21 | — | — | WO | disclosed |
| US-20210323926-A1 | Novel Lymphoid-Specific Tyrosine Phosphatase (LYP) Inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323926-A1 | Novel Lymphoid-Specific Tyrosine Phosphatase (LYP) Inhibitors | PTPN22, PTPN1, PTPRCAP | PTPN22 1/4885F10 4505/4885PRSS1 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.