Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399386 | 0.89 | PKM (0.47) | ELANEPKMCDK9DYRK1AKDM4E | |
| SCHEMBL2394762 | 0.79 | KDM4E (0.47) | ELANEPKMKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2397310 | 0.75 | KDM4E (0.42) | KDM4EHPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9677048 | 0.68 | NPSR1 (0.49) | PKMKDM4EHPGDNPSR1ALDH1A1 | |
| SCHEMBL6957142 | 0.68 | NPSR1 (0.49) | ELANEPKMCDK9DYRK1AKDM4E | |
| SCHEMBL15515380 | 0.68 | ELANE (0.40) | ELANEKDM4ELMNAL3MBTL1 | |
| SCHEMBL24020336 | 0.67 | KDM4E (0.40) | PKMKDM4ENPSR1 | |
| SCHEMBL2399383 | 0.67 | KDM4E (0.60) | PKMKDM4EHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL24020341 | 0.67 | KDM4E (0.41) | CDK9DYRK1AKDM4ENPSR1 | |
| SCHEMBL10626672 | 0.66 | NPSR1 (0.46) | PKMKDM4EHPGDNPSR1GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542533-B1 | FLUORALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THEIR USE FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER IP GMBH (DE) | 2014-09-10 | — | — | EP | disclosed |
| EP-2542533-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | Bayer Intellectual Property GmbH (DE) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011107504-A1 | FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2011-09-09 | — | — | WO | disclosed |