Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15515379 | 0.79 | MAOB (0.44) | ELANEKDM4ELMNATOP2A | |
| SCHEMBL15515894 | 0.70 | DYRK1A (0.39) | KDM4EL3MBTL1LMNAPOLB | |
| SCHEMBL3123413 | 0.68 | ELANE (0.54) | ELANEKDM4ELMNAPOLB | |
| SCHEMBL2394770 | 0.68 | ELANE (0.37) | ELANEKDM4EL3MBTL1LMNA | |
| SCHEMBL19029855 | 0.66 | PGK1 (0.36) | ELANEKDM4EL3MBTL1 | |
| SCHEMBL15515654 | 0.66 | AGPAT2 (0.42) | KDM4ELMNAPOLBTOP2A | |
| SCHEMBL317958 | 0.62 | NQO2 (0.58) | KDM4EL3MBTL1LMNAMETAP2METAP1 | |
| SCHEMBL3415803 | 0.62 | LMNA (0.71) | KDM4EL3MBTL1USP2LMNAMETAP2 | |
| SCHEMBL9203792 | 0.62 | KDM4E (0.43) | ELANEKDM4EL3MBTL1LMNAEDNRA | |
| SCHEMBL8708513 | 0.62 | CNR2 (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892345-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014037340-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2014-03-13 | — | — | WO | disclosed |