SCHEMBL23947740

SCHEMBL23947740

COc1ccc(C2c3ccsc3CCN2CC(=O)N2CCN(C(=O)CCl)C(C)C2)cc1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.49
LHCGR P22888 11/20 0.48
CNR1 P21554 1/20 0.45
HHAT Q5VTY9 2/20 0.38
MAPK1 P28482 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23947745 0.83 LHCGR (0.48) LHCGRCNR1HHATNPSR1
SCHEMBL23947757 0.82 HHAT (0.39) LHCGRHHAT
SCHEMBL29763655 0.82 HHAT (0.39) LHCGRHHAT
SCHEMBL8176067 0.69 LHCGR (0.59) POLBLHCGRCNR1MAPK1NPSR1
SCHEMBL7891790 0.69 POLB (0.69) POLBLHCGRCNR1HHATMAPK1
SCHEMBL7889844 0.69 LHCGR (0.69) POLBLHCGRCNR1MAPK1NPSR1
Hydrochloric Acid SCHEMBL7886002 0.69 LHCGR (0.58) POLBLHCGRCNR1MAPK1NPSR1
SCHEMBL23947759 0.68 HHAT (0.40) LHCGRHHAT
SCHEMBL29763691 0.68 HHAT (0.40) LHCGRHHAT
SCHEMBL23947761 0.68 LHCGR (0.50) LHCGRHHATNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12533339-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2026-01-27 US disclosed
US-20240173291-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2024-05-30 US disclosed
US-11877999-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2024-01-23 US disclosed
US-11628158-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2023-04-18 US disclosed
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2023-02-16 US disclosed
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2023-02-16 US disclosed
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2022-05-12 US disclosed
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2022-05-12 US disclosed
WO-2021212010-A2 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY (US) 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI POLB 30/4885LHCGR 3029/4885CNR1 4715/4885
US-11877999-B2 Small molecule antiviral drug treatment for human papillomavirus infections TP53, EIF2AK2, POLI POLB 30/4885LHCGR 3029/4885CNR1 4715/4885
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI POLB 30/4885LHCGR 3029/4885CNR1 4715/4885
US-12533339-B2 Small molecule antiviral drug treatment for human papillomavirus infections CCND3, CCND1, TPD52L2 POLB 424/4885LHCGR 630/4885CNR1 508/4885
US-20240173291-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI POLB 30/4885LHCGR 3029/4885CNR1 4715/4885
US-11628158-B2 Small molecule antiviral drug treatment for human papillomavirus infections TP53, EIF2AK2, POLI POLB 30/4885LHCGR 3029/4885CNR1 4715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.