SCHEMBL23948195

SCHEMBL23948195

Cc1cc(C#N)ccc1Nc1ncc2c(n1)n(C1CC3COCC3C1)c(=O)n2C

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 20/20 0.56
CSF1R P07333 2/20 0.56
TTK P33981 2/20 0.56
PIK3CA P42336 1/20 0.54
MTOR P42345 1/20 0.54
KCNH2 Q12809 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23948616 1.00 PRKDC (0.56) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL23948191 0.92 PRKDC (0.61) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL23948473 0.88 PRKDC (0.69) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL25057401 0.86 PRKDC (0.74) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL23948187 0.84 PRKDC (0.63) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL29501864 0.84 PRKDC (0.63) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL28701964 0.84 PRKDC (0.63) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL23948620 0.84 PRKDC (0.63) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL23948112 0.84 PRKDC (0.64) PRKDCCSF1RTTKPIK3CAMTOR
SCHEMBL29501928 0.82 PRKDC (0.64) PRKDCCSF1RTTKPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315834-B Imidazolone derivatives and their use in medicine 成都百裕制药股份有限公司 2024-01-05 CN disclosed
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) 2023-06-01 US disclosed
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) 2023-06-01 US disclosed
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) 2023-06-01 US disclosed
EP-4137491-A1 IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) 2023-02-22 EP disclosed
CN-114315834-A Imidazolidinone derivatives and their use in medicaments 成都百裕制药股份有限公司 2022-04-12 CN disclosed
WO-2021209055-A1 IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE 成都百裕制药股份有限公司 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF SYMPK, PAICS, CYP2C9 PRKDC 316/4885CSF1R 2127/4885TTK 1365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.