Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768875 | 0.99 | TSHR (0.37) | TSHRHPGDTHRBTHRAGLS2 | |
| Bromide SCHEMBL2395982 | 0.84 | TSHR (0.35) | TSHR | |
| SCHEMBL20496022 | 0.81 | TSHR (0.40) | TSHRHPGDTHRBTHRA | |
| Hydrochloric Acid SCHEMBL20496011 | 0.80 | TSHR (0.40) | TSHRHPGDTHRBTHRA | |
| SCHEMBL31456184 | 0.79 | TSHR (0.50) | TSHRHPGDTHRBTHRACA2 | |
| SCHEMBL31742396 | 0.79 | TSHR (0.50) | TSHRHPGDTHRBTHRACA2 | |
| SCHEMBL867648 | 0.79 | TSHR (0.50) | TSHRHPGDTHRBTHRACA2 | |
| SCHEMBL10080799 | 0.79 | TSHR (0.50) | TSHRHPGDTHRBTHRACA2 | |
| SCHEMBL7537024 | 0.79 | TSHR (0.50) | TSHRHPGDTHRBTHRACA2 | |
| SCHEMBL2688012 | 0.77 | TSHR (0.48) | TSHRHPGDTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623971-B2 | Freestanding ion gel and method for preparing the same | Research & Business Foundation Sungkyunkwan University (KR) | 2023-04-11 | — | — | US | claimed |
| US-20210054127-A1 | FREESTANDING ION GEL AND METHOD FOR PREPARING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2021-02-25 | — | — | US | claimed |
| US-11623971-B2 | Freestanding ion gel and method for preparing the same | Research & Business Foundation Sungkyunkwan University (KR) | 2023-04-11 | — | — | US | disclosed |
| US-20210054127-A1 | FREESTANDING ION GEL AND METHOD FOR PREPARING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2021-02-25 | — | — | US | disclosed |
| US-9837181-B2 | Processes for nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY (US) | 2017-12-05 | — | — | US | disclosed |
| US-20150086721-A1 | PROCESSES FOR NANOPARTICLE DISPERSIONS WITH IONIC LIQUID-BASED STABILIZERS | EASTERN MICHIGAN UNIVERSITY | 2015-03-26 | — | — | US | disclosed |
| US-8920682-B2 | Nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY (US) | 2014-12-30 | — | — | US | disclosed |
| EP-2583940-A1 | Stabilization of carbon nanomaterials and hydrophobic compounds by copolymers | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-20110233458-A1 | Nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY Office of Research Development (US) | 2011-09-29 | — | — | US | disclosed |
| CN-101619115-B | High-temperature proton-exchange polymer film and preparation method thereof | UNIV SUZHOU | 2011-09-21 | — | — | CN | disclosed |
| US-7759401-B2 | Nanoporous and microporous solvogels and nanolatexes by microemulsion polymerization | EASTERN MICHIGAN UNIVERSITY (US) | 2010-07-20 | — | — | US | disclosed |
| CN-101619115-A | High-temperature proton-exchange polymer film and preparation method thereof | UNIV SUZHOU | 2010-01-06 | — | — | CN | disclosed |
| US-20090176915-A1 | NANOPOROUS AND MICROPOROUS SOLVOGELS AND NONOLATEXES BY MICROEMULSION POLYMERIZATION | EASTERN MICHIGAN UNIVERSITY | 2009-07-09 | — | — | US | disclosed |