SCHEMBL867648

SCHEMBL867648

C=CC(=O)OC(CCCC)CCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
HPGD P15428 1/20 0.47
CA2 P00918 1/20 0.42
THRB P10828 2/20 0.41
ZDHHC20 Q5W0Z9 2/20 0.41
ZDHHC2 Q9UIJ5 2/20 0.41
CTSK P43235 1/20 0.41
GPR84 Q9NQS5 3/20 0.40
THRA P10827 1/20 0.40
FFAR1 O14842 1/20 0.40
MAPT P10636 2/20 0.40
ZDHHC7 Q9NXF8 1/20 0.40
MAPK1 P28482 1/20 0.40
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
FAAH O00519 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10080799 1.00 TSHR (0.50) TSHRHPGDCA2THRBZDHHC20
SCHEMBL31456184 1.00 TSHR (0.50) TSHRHPGDCA2THRBZDHHC20
SCHEMBL7537024 1.00 TSHR (0.50) TSHRHPGDCA2THRBZDHHC20
SCHEMBL31742396 1.00 TSHR (0.50) TSHRHPGDCA2THRBZDHHC20
SCHEMBL18134827 0.98 TSHR (0.48) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL7125959 0.98 TSHR (0.48) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL7649106 0.98 TSHR (0.48) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL6357521 0.98 TSHR (0.48) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL21647292 0.98 TSHR (0.48) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL7864075 0.98 TSHR (0.51) TSHRHPGDCA2THRBZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 US disclosed
US-10696795-B2 Photoaligning materials Rolic Technologies AG (CH) 2020-06-30 US disclosed
EP-3374467-B1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC TECH AG (CH) 2020-04-15 EP disclosed
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 US disclosed
US-20180319939-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2018-11-08 US disclosed
US-20180320072-A1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS Rolic Technologies AG (CH) 2018-11-08 US disclosed
EP-3374416-A1 PHOTOALIGNMENT MATERIALS ROLIC Technologies AG (CH) 2018-09-19 EP disclosed
EP-3374467-A1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC Technologies AG (CH) 2018-09-19 EP disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group DDC, ALAD, DYNC1LI1 TSHR 4828/4885HPGD 1068/4885CA2 2515/4885
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 TSHR 4828/4885HPGD 1068/4885CA2 2515/4885
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD TSHR 3933/4885HPGD 852/4885CA2 2945/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 TSHR 4598/4885HPGD 3943/4885CA2 1251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.