Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2394896 | 0.84 | TSHR (0.36) | TSHR | |
| SCHEMBL27768875 | 0.83 | TSHR (0.37) | TSHR | |
| SCHEMBL19456905 | 0.80 | TSHR (0.45) | TSHRPRKCAPRKCD | |
| SCHEMBL13236320 | 0.77 | TSHR (0.54) | TSHR | |
| Acrylic Acid SCHEMBL28303812 | 0.76 | ZDHHC20 (0.36) | — | |
| Hydrochloric Acid SCHEMBL28597536 | 0.76 | TSHR (0.53) | TSHR | |
| SCHEMBL11460175 | 0.75 | TSHR (0.49) | TSHRPRKCAPRKCD | |
| SCHEMBL6046850 | 0.75 | TSHR (0.49) | TSHRPRKCAPRKCD | |
| SCHEMBL665164 | 0.75 | TSHR (0.49) | TSHRPRKCAPRKCD | |
| SCHEMBL4418169 | 0.75 | TSHR (0.49) | TSHRPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837181-B2 | Processes for nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY (US) | 2017-12-05 | — | — | US | disclosed |
| US-20150086721-A1 | PROCESSES FOR NANOPARTICLE DISPERSIONS WITH IONIC LIQUID-BASED STABILIZERS | EASTERN MICHIGAN UNIVERSITY | 2015-03-26 | — | — | US | disclosed |
| US-8920682-B2 | Nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY (US) | 2014-12-30 | — | — | US | disclosed |
| US-20110233458-A1 | Nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY Office of Research Development (US) | 2011-09-29 | — | — | US | disclosed |