Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | FRK | P42685 | 1/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950293 | 0.87 | PTGS2 (0.42) | EGLN1TOP1PIM1PTGS1PTGS2 | |
| SCHEMBL23950296 | 0.87 | GRM2 (0.38) | EGLN1TOP1PIM1MAPTPTGS1 | |
| SCHEMBL23950768 | 0.86 | EGLN1 (0.38) | EGLN1TOP1PIM1MAPTPTGS1 | |
| SCHEMBL23950264 | 0.86 | EGLN1 (0.38) | EGLN1TOP1PIM1MAPTPTGS1 | |
| SCHEMBL23390502 | 0.86 | SMN1; SMN2 (0.38) | EGLN1TOP1PIM1MAPTPTGS1 | |
| SCHEMBL23951123 | 0.85 | PIM1 (0.37) | EGLN1TOP1PIM1MAPTPTGS1 | |
| SCHEMBL30102064 | 0.85 | PIM1 (0.37) | EGLN1TOP1PIM1MAPTPTGS1 | |
| SCHEMBL26294729 | 0.85 | HSP90AA1 (0.39) | PIM1PTGS1PTGS2GRM2 | |
| SCHEMBL23950531 | 0.84 | PIM1 (0.41) | EGLN1TOP1PIM1MAPTPTGS1 | |
| SCHEMBL23390067 | 0.83 | AHR (0.45) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021210970-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR MODULATORS | DONG-A ST CO., LTD. (KR) | 2021-10-21 | — | — | WO | disclosed |