SCHEMBL2395085

SCHEMBL2395085

CC(C)(C)c1ccc(OC(=O)c2cccc(C(=O)Oc3ccc(C(C)(C)C)cc3)c2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.78
TDP1 Q9NUW8 2/20 0.78
L3MBTL1 Q9Y468 1/20 0.78
ALDH1A1 P00352 2/20 0.66
THRB P10828 1/20 0.66
KMT2A Q03164 5/20 0.61
MEN1 O00255 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
PRSS1 P07477 1/20 0.56
ACR P10323 1/20 0.56
NPSR1 Q6W5P4 2/20 0.55
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
HIF1A Q16665 1/20 0.49
RAB9A P51151 2/20 0.49
NR4A1 P22736 1/20 0.48
NR4A2 P43354 1/20 0.48
NR4A3 Q92570 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917962 0.95 MAPT (0.71) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL27636737 0.91 MAPT (0.69) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL21771874 0.89 MAPT (0.68) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL8210174 0.88 MAPT (1.00) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL2396251 0.85 MAPT (0.83) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL14062435 0.85 MAPT (0.83) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL2518984 0.85 MAPT (0.67) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL10875111 0.84 MAPT (0.56) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL1786807 0.83 MAPT (0.69) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL28565618 0.83 MDH1 (0.57) MAPTTDP1L3MBTL1ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110475798-B Active ester composition DIC株式会社 2024-08-23 CN disclosed
CN-109476821-B Active ester resin and cured product thereof DIC株式会社 2021-05-07 CN disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885TDP1 3534/4885L3MBTL1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.