Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 6/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859006 | 0.94 | MAPT (0.55) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL14241103 | 0.94 | MAPT (0.51) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| Terephthalic Acid SCHEMBL361198 | 0.92 | MAPT (0.52) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL13184050 | 0.92 | KMT2A (0.62) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL21681864 | 0.91 | ESR1 (0.60) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL29905110 | 0.91 | ESR1 (0.60) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL13184039 | 0.90 | ESR1 (0.64) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL13184001 | 0.90 | KDM4E (0.50) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL2518984 | 0.89 | MAPT (0.67) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL12337501 | 0.89 | MAPT (0.71) | MAPTTDP1L3MBTL1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127842-B1 | DIPHENOL MONOESTERS OF CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE IN THE PREPARATION OF POLYESTER CARBONATES, POLYESTER CARBONATES OBTAINED ACCORDING TO THE INVENTION AND FLAME-RETARDANT MOULDING COMPOUNDS CONTAINING THESE POLYESTER CARBONATES | BAYER AG (DE) | 1986-07-02 | — | — | EP | disclosed |