Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387203 | 0.84 | — | — | |
| SCHEMBL637868 | 0.84 | — | — | |
| Acetic Acid SCHEMBL3180178 | 0.83 | ALDH1A1 (0.34) | ALDH1A1MAPTPTGS1FFAR3LCK | |
| Acetic Acid SCHEMBL674733 | 0.83 | ALDH1A1 (0.34) | ALDH1A1MAPTPTGS1FFAR3LCK | |
| Hydrochloric Acid SCHEMBL17648622 | 0.81 | ALDH1A1 (0.39) | ALDH1A1DPP4 | |
| SCHEMBL4270514 | 0.78 | ALDH1A1 (0.37) | ALDH1A1DPP4 | |
| SCHEMBL5579824 | 0.76 | ALDH1A1 (0.35) | ALDH1A1DPP4 | |
| Acetic Acid SCHEMBL6707542 | 0.75 | FFAR3 (0.47) | ALDH1A1PTGS1FFAR3LCKFYN | |
| Acetic Acid SCHEMBL5570292 | 0.75 | FFAR3 (0.47) | ALDH1A1PTGS1FFAR3LCKFYN | |
| Acetic Acid SCHEMBL1536717 | 0.75 | FFAR3 (0.47) | ALDH1A1PTGS1FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017563-B2 | Diverting compositions, fluid loss control pills, and breakers thereof | M-I L.L.C. (US) | 2011-09-13 | — | — | US | claimed |
| EP-1991634-A1 | DIVERTING COMPOSITIONS, FLUID LOSS CONTROL PILLS, AND BREAKERS THEREOF | M-I L.L.C. (US) | 2008-11-19 | — | — | EP | claimed |
| WO-2007104054-A1 | DIVERTING COMPOSITIONS, FLUID LOSS CONTROL PILLS, AND BREAKERS THEREOF | M-I LLC (US) | 2007-09-13 | — | — | WO | claimed |
| US-20070213233-A1 | DIVERTING COMPOSITIONS, FLUID LOSS CONTROL PILLS, AND BREAKERS THEREOF | M-I LLC (US) | 2007-09-13 | — | — | US | claimed |
| US-8017563-B2 | Diverting compositions, fluid loss control pills, and breakers thereof | M-I L.L.C. (US) | 2011-09-13 | — | — | US | disclosed |
| US-7762657-B2 | Inkjet ink, processing liquid for inkjet ink, ink set for inkjet ink, ink tank for inkjet ink, inkjet recording method and inkjet recording apparatus | FUJI XEROX CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| EP-1991634-A1 | DIVERTING COMPOSITIONS, FLUID LOSS CONTROL PILLS, AND BREAKERS THEREOF | M-I L.L.C. (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007104054-A1 | DIVERTING COMPOSITIONS, FLUID LOSS CONTROL PILLS, AND BREAKERS THEREOF | M-I LLC (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070213233-A1 | DIVERTING COMPOSITIONS, FLUID LOSS CONTROL PILLS, AND BREAKERS THEREOF | M-I LLC (US) | 2007-09-13 | — | — | US | disclosed |
| US-7182452-B2 | Ink set for ink jet recording, ink jet recording method, and ink jet recording apparatus | FUJI XEROX CO., LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20060293410-A1 | Inkjet ink, processing liquid for inkjet ink, ink set for inkjet ink, ink tank for inkjet ink, inkjet recording method and inkjet recording apparatus | FUJI XEROX CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| US-7018459-B2 | Ink set for ink-jet recording, ink-jet recording method and ink-jet recording apparatus | FUJI XEROX CO., LTD. (JP) | 2006-03-28 | — | — | US | disclosed |
| US-20050012796-A1 | Ink set for ink-jet recording, ink-jet recording method and ink-jet recording apparatus | FUJI XEROX CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| US-20040257418-A1 | Ink set for ink jet recording, ink jet recording method, and ink jet recording apparatus | FUJI XEROX CO., LTD. (JP) | 2004-12-23 | — | — | US | disclosed |