Acetic Acid

Acetic Acid

SCHEMBL674733

CC(=O)O.CC(=O)O.CC(=O)O.CC(=O)O.CC(C)(O)C(N)CN

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 known ✓ P29474 1/20 0.30
NOS1 known ✓ P29475 1/20 0.30
NOS2 known ✓ P35228 1/20 0.30
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34
PTGS1 P23219 1/20 0.34
ADRA1A P35348 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
TSHR P16473 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
GABRR1 P24046 4/20 0.31
LMNA P02545 1/20 0.31
GRIK1 P39086 2/20 0.31
CACNA2D1 P54289 2/20 0.30
CACNB3 P54284 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL3180178 0.86 ALDH1A1 (0.34) ALDH1A1MAPTPTGS1ADRA1AKDM4E
Acetic Acid SCHEMBL2395572 0.83 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1ADRA1AKDM4E
Isopropyl Alcohol SCHEMBL561671 0.80 ALDH1A1 (0.38) ALDH1A1LMNA
Acetic Acid SCHEMBL16286408 0.74 GABRR1 (0.31) GABRR1LMNA
Acetic Acid SCHEMBL1536717 0.73 FFAR3 (0.47) ALDH1A1PTGS1ADRA1AFFAR3LCK
Acetic Acid SCHEMBL5570292 0.73 FFAR3 (0.47) ALDH1A1PTGS1ADRA1AFFAR3LCK
Acetic Acid SCHEMBL6707542 0.73 FFAR3 (0.47) ALDH1A1PTGS1ADRA1AFFAR3LCK
SCHEMBL7344981 0.73 ADRA1A (0.40) ALDH1A1MAPTPTGS1ADRA1AHMGCR
SCHEMBL5478252 0.73 ADRA1A (0.46) ALDH1A1ADRA1AKDM4EHMGCRCHRM1
Acetic Acid SCHEMBL8817349 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3455269-B1 IMPLANTABLE GLUCOSE SENSORS HAVING A BIOSTABLE SURFACE EVONIK CANADA INC (CA) 2023-09-20 EP disclosed
US-20200123367-A1 PLASTICIZED PVC ADMIXTURES WITH SURFACE MODIFYING MACROMOLECULES AND ARTICLES MADE THEREFROM INTERFACE BIOLOGICS, INC. (CA) 2020-04-23 US disclosed
US-10557030-B2 Plasticized PVC admixtures with surface modifying macromolecules and articles made therefrom Evonik Canada Inc. (CA) 2020-02-11 US disclosed
EP-3529300-A1 PLASTICIZED PVC ADMIXTURES WITH SURFACE MODIFYING MACROMOLECULES AND ARTICLES MADE THEREFROM Interface Biologics, Inc. (CA) 2019-08-28 EP disclosed
US-20190248995-A1 PLASTICIZED PVC ADMIXTURES WITH SURFACE MODIFYING MACROMOLECULES AND ARTICLES MADE THEREFROM INTERFACE BIOLOGICS, INC. (CA) 2019-08-15 US disclosed
US-20190142317-A1 IMPLANTABLE GLUCOSE SENSORS HAVING A BIOSTABLE SURFACE Evonik Canada Inc. (CA) 2019-05-16 US disclosed
EP-3455269-A1 IMPLANTABLE GLUCOSE SENSORS HAVING A BIOSTABLE SURFACE Interface Biologics Inc. (CA) 2019-03-20 EP disclosed
WO-2018075663-A1 PLASTICIZED PVC ADMIXTURES WITH SURFACE MODIFYING MACROMOLECULES AND ARTICLES MADE THEREFROM INTERFACE BIOLOGICS, INC. (CA) 2018-04-26 WO disclosed
WO-2017195035-A1 IMPLANTABLE GLUCOSE SENSORS HAVING A BIOSTABLE SURFACE INTERFACE BIOLOGICS, INC. (CA) 2017-11-16 WO disclosed
US-9764884-B2 Packaging materials including a barrier film INTERFACE BIOLOGICS, INC. (CA) 2017-09-19 US disclosed
EP-2102258-B1 SURFACE MODIFYING MACROMOLECULES WITH HIGH DEGRADATION TEMPERATURES AND USES THEREOF INTERFACE BIOLOGICS INC (CA) 2016-10-19 EP disclosed
US-20160096936-A1 PACKAGING MATERIALS INCLUDING A BARRIER FILM Evonik Canada Inc. (CA) 2016-04-07 US disclosed
US-8338537-B2 Surface modifying macromolecules with high degradation temperatures and uses thereof INTERFACE BIOLOGICS INC. (CA) 2012-12-25 US disclosed
US-20120220724-A1 SURFACE MODIFYING MACROMOLECULES WITH HIGH DEGRADATION TEMPERATURES AND USES THEREOF INTERFACE BIOLOGICS INC. (CA) 2012-08-30 US disclosed
US-8178620-B2 Surface modifying macromolecules with high degradation temperatures and uses thereof INTERFACE BIOLOGICS INC. (CA) 2012-05-15 US disclosed
US-8071683-B2 Surface modifying macromolecules with high degradation temperatures and uses thereof INTERFACE BIOLOGICS INC. (CA) 2011-12-06 US disclosed
US-20110271961-A1 SURFACE MODIFYING MACROMOLECULES WITH HIGH DEGRADATION TEMPERATURES AND USES THEREOF INTERFACE BIOLOGICS INC. (CA) 2011-11-10 US disclosed
EP-2102258-A1 SURFACE MODIFYING MACROMOLECULES WITH HIGH DEGRADATION TEMPERATURES AND USES THEREOF Interface Biologics Inc. (CA) 2009-09-23 EP disclosed
US-20080228253-A1 Surface modifying macromolecules with high degradation temperatures and uses thereof Evonik Canada Inc. (CA) 2008-09-18 US disclosed
WO-2008076345-A1 SURFACE MODIFYING MACROMOLECULES WITH HIGH DEGRADATION TEMPERATURES AND USES THEREOF INTERFACE BIOLOGICS INC. (CA) 2008-06-26 WO disclosed