Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15604265 | 1.00 | SLC1A2 (0.43) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL12462681 | 1.00 | SLC1A2 (0.43) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL13300681 | 0.86 | SLC15A1 (0.55) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL13857618 | 0.86 | SLC15A1 (0.55) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL13484492 | 0.86 | SLC15A1 (0.55) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL13300673 | 0.84 | OPRM1 (0.56) | SLC1A2SLC1A1GRIK1GRIK2TP53 | |
| SCHEMBL17173878 | 0.84 | OPRM1 (0.56) | SLC1A2SLC1A1GRIK1GRIK2TP53 | |
| SCHEMBL14133799 | 0.84 | OPRM1 (0.56) | SLC1A2SLC1A1GRIK1GRIK2TP53 | |
| SCHEMBL23845046 | 0.83 | SLC1A3 (0.42) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL20383849 | 0.82 | OPRM1 (0.54) | SLC1A2SLC1A1GRIK1GRIK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3900742-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | Seagen Inc. (US) | 2021-10-27 | — | — | EP | disclosed |