Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20879978 | 0.92 | EPHX1 (0.37) | EPHX1 | |
| SCHEMBL15984870 | 0.92 | EPHX1 (0.37) | EPHX1RECQLSMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL16774245 | 0.83 | RECQL (0.33) | EPHX1RECQLSMN1; SMN2CA1CA2 | |
| SCHEMBL14756359 | 0.78 | EPHX1 (0.46) | EPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL15984918 | 0.77 | CA1 (0.41) | RECQLSMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL12022309 | 0.77 | CA1 (0.43) | SMN1; SMN2ALDH1A1CA1CA2MEN1 | |
| SCHEMBL25668219 | 0.76 | GAA (0.31) | ALDH1A1CA1CA2 | |
| SCHEMBL813534 | 0.74 | ALDH1A1 (0.30) | EPHX1ALDH1A1 | |
| SCHEMBL21440819 | 0.74 | CA1 (0.37) | RECQLALDH1A1CA1CA2 | |
| SCHEMBL20887524 | 0.74 | CA1 (0.37) | RECQLALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596805-B1 | Prodrug comprising a drug-linker conjugate | ASCENDIS PHARMA AS (DK) | 2021-10-27 | — | — | EP | disclosed |