Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20879978 | 0.81 | EPHX1 (0.37) | EPHX1 | |
| SCHEMBL17285643 | 0.79 | — | — | |
| SCHEMBL13144610 | 0.77 | KDM4E (0.40) | ALDH1A1EPHX1 | |
| SCHEMBL23955941 | 0.74 | EPHX1 (0.32) | ALDH1A1EPHX1 | |
| SCHEMBL2616818 | 0.73 | — | — | |
| SCHEMBL17913964 | 0.72 | — | — | |
| SCHEMBL10131957 | 0.72 | CA1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL64863 | 0.72 | — | — | |
| SCHEMBL20880003 | 0.71 | PAOX (0.39) | ALDH1A1EPHX1 | |
| SCHEMBL23140063 | 0.70 | SMN1; SMN2 (0.44) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962784-B2 | Isocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | ETHICON, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8470954-B2 | Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | ETHICON, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-8324292-B2 | Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant | ETHICON, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-8071663-B2 | Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant | ETHICON, INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-7968668-B2 | Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | ETHICON INC. (US) | 2011-06-28 | — | — | US | disclosed |
| US-20100158849-A1 | ISOCYANATE TERMINATED MACROMER AND FORMULATION THEREOF FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ETHICON, INC. | 2010-06-24 | — | — | US | disclosed |
| US-7728097-B2 | Method of making a diisocyanate terminated macromer | ETHICON, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20090222038-A1 | MEDICALLY ACCEPTABLE FORMULATION OF A DIISOCYANATE TERMINATED MACROMER FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ETHICON, INC. | 2009-09-03 | — | — | US | disclosed |
| US-20090221731-A1 | MEDICALLY ACCEPTABLE FORMULATION OF A DIISOCYANATE TERMINATED MACROMER FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ETHICON, INC. | 2009-09-03 | — | — | US | disclosed |
| US-20070276121-A1 | DIISOCYANATE TERMINATED MACROMER AND FORMULATION THEREOF FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ETHICON, INC. | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158849-A1 | ISOCYANATE TERMINATED MACROMER AND FORMULATION THEREOF FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ICAM1, ILK, MACF1 | ALDH1A1 517/4885TDP1 1867/4885EPHX1 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.