Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483721 | 0.90 | HTT (0.64) | HTTTSHRKMT2AL3MBTL1BRD4 | |
| SCHEMBL26417076 | 0.90 | HTT (0.64) | HTTTSHRKMT2AL3MBTL1BRD4 | |
| SCHEMBL13990159 | 0.83 | L3MBTL1 (0.52) | HTTTSHRKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL29315261 | 0.82 | HTT (0.56) | HTTTSHRKMT2AL3MBTL1BRD4 | |
| SCHEMBL6268376 | 0.82 | KMT2A (0.65) | HTTTSHRKMT2AL3MBTL1BRD4 | |
| SCHEMBL13544865 | 0.82 | TSHR (0.56) | HTTTSHRKMT2AL3MBTL1BRD4 | |
| SCHEMBL28834724 | 0.82 | HTT (0.56) | HTTTSHRKMT2AL3MBTL1BRD4 | |
| SCHEMBL28921174 | 0.81 | HPGD (0.62) | HTTTSHRL3MBTL1CA1CA9 | |
| SCHEMBL6566957 | 0.81 | TSHR (0.55) | HTTTSHRKMT2AL3MBTL1BRD4 | |
| SCHEMBL3854000 | 0.81 | BRD4 (0.55) | HTTTSHRKMT2AL3MBTL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596805-B1 | Prodrug comprising a drug-linker conjugate | ASCENDIS PHARMA AS (DK) | 2021-10-27 | — | — | EP | disclosed |