Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483721 | 0.90 | HTT (0.64) | TSHRHTTKMT2AL3MBTL1BRD4 | |
| SCHEMBL26417076 | 0.90 | HTT (0.64) | TSHRHTTKMT2AL3MBTL1BRD4 | |
| SCHEMBL1063005 | 0.85 | TSHR (0.66) | TSHRHTTL3MBTL1ADRA1DADRA1A | |
| SCHEMBL6903284 | 0.84 | TSHR (0.58) | TSHRHTTKMT2AALDH1A1KDM4E | |
| SCHEMBL13544865 | 0.82 | TSHR (0.56) | TSHRHTTKMT2AL3MBTL1BRD4 | |
| SCHEMBL6268376 | 0.82 | KMT2A (0.65) | TSHRHTTKMT2AL3MBTL1BRD4 | |
| SCHEMBL28834724 | 0.82 | HTT (0.56) | TSHRHTTKMT2AL3MBTL1BRD4 | |
| SCHEMBL2129167 | 0.82 | TSHR (0.47) | TSHRHTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL29315261 | 0.82 | HTT (0.56) | TSHRHTTKMT2AL3MBTL1BRD4 | |
| SCHEMBL5702819 | 0.82 | TSHR (0.83) | TSHRHTTL3MBTL1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854177-B1 | Ink compositions | XEROX CORP (US) | 2004-03-31 | — | — | EP | claimed |
| EP-0854177-B1 | Ink compositions | XEROX CORP (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002020437-A2 | BASIC COMPOUNDS CONTAINING TERTIARY AMIDES WITH ACTIVITY ON TACHYKININ RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2002-03-14 | — | — | WO | disclosed |