Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 12/20 | 0.36 |
| ▸ | JAK1 | P23458 | 12/20 | 0.36 |
| ▸ | TYK2 | P29597 | 12/20 | 0.36 |
| ▸ | JAK3 | P52333 | 12/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956582 | 0.85 | LMNA (0.30) | — | |
| SCHEMBL21264906 | 0.83 | JAK2 (0.37) | JAK2JAK1TYK2JAK3STING1 | |
| SCHEMBL23956666 | 0.83 | S1PR1 (0.36) | — | |
| SCHEMBL23956636 | 0.83 | CARM1 (0.32) | — | |
| SCHEMBL23956588 | 0.82 | OPRM1 (0.31) | — | |
| SCHEMBL23956637 | 0.74 | POLB (0.33) | KMT2A | |
| SCHEMBL30423852 | 0.73 | JAK2 (0.39) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL21750109 | 0.73 | JAK2 (0.39) | JAK2JAK1TYK2JAK3KMT2A | |
| SCHEMBL24286075 | 0.72 | MEN1 (0.32) | KMT2A | |
| SCHEMBL24044908 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515921-B1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-10-27 | — | — | EP | disclosed |