Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | BLVRB | P30043 | 1/20 | 0.52 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25828324 | 0.94 | XDH (0.54) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL23957016 | 0.92 | XDH (0.52) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL23956950 | 0.85 | XDH (0.46) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL25828169 | 0.85 | XDH (0.69) | XDHABCC4ABCB11PGRCHRM1 | |
| Hydrochloric Acid SCHEMBL29217433 | 0.84 | XDH (0.68) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL25828182 | 0.84 | XDH (0.67) | XDHABCC4ABCB11PGRCHRM1 | |
| Hydrochloric Acid SCHEMBL23932805 | 0.83 | XDH (0.66) | XDHABCC4ABCB11PGRCHRM1 | |
| Hydrochloric Acid SCHEMBL31006731 | 0.83 | XDH (0.66) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL23957002 | 0.81 | NPC1 (0.45) | XDHABCC4ABCB11PGRCHRM1 | |
| Hydrochloric Acid SCHEMBL29217420 | 0.80 | XDH (0.44) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4140989-A1 | NOVEL 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Hexapharmatec Co., Ltd. (KR) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021215624-A1 | NOVEL 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | (주)헥사파마텍 (KR) | 2021-10-28 | — | — | WO | disclosed |