Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 7/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | BLVRB | P30043 | 1/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29217420 | 0.99 | XDH (0.44) | NPC1HPGDXDHABCC4ABCB11 | |
| SCHEMBL23956948 | 0.90 | XDH (0.46) | NPC1HPGDXDHABCC4ABCB11 | |
| Hydrochloric Acid SCHEMBL29217418 | 0.89 | XDH (0.46) | NPC1HPGDXDHABCC4ABCB11 | |
| SCHEMBL29217432 | 0.88 | PPID (0.49) | NPC1HPGDXDHABCC4ABCB11 | |
| Hydrochloric Acid SCHEMBL25263331 | 0.87 | PPID (0.49) | NPC1HPGDXDHABCC4ABCB11 | |
| SCHEMBL25828324 | 0.86 | XDH (0.54) | NPC1HPGDXDHABCC4ABCB11 | |
| SCHEMBL25828169 | 0.84 | XDH (0.69) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL23957007 | 0.83 | HPGD (0.51) | NPC1HPGDEGLN1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29217433 | 0.83 | XDH (0.68) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL23957016 | 0.82 | XDH (0.52) | NPC1HPGDXDHABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219908-A1 | NOVEL 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | HEXAPHARMATEC CO., LTD. (KR) | 2023-07-13 | — | — | US | disclosed |
| WO-2021215624-A1 | NOVEL 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | (주)헥사파마텍 (KR) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219908-A1 | NOVEL 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | WEE2, WEE1, NOTUM | NPC1 727/4885HPGD 2144/4885XDH 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.