Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23957002 | 0.83 | NPC1 (0.45) | HPGDNPC1KMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29217420 | 0.83 | XDH (0.44) | HPGDNPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25828324 | 0.80 | XDH (0.54) | HPGDNPC1KMT2AMEN1MAPT | |
| SCHEMBL3399977 | 0.80 | TSHR (0.53) | HPGDNPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3401375 | 0.79 | SMYD2 (0.51) | HPGDNPC1SMN1; SMN2GAATP53 | |
| SCHEMBL23956927 | 0.79 | CD274 (0.52) | HPGDKMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL25828169 | 0.78 | XDH (0.69) | — | |
| SCHEMBL3396720 | 0.78 | MAPT (0.56) | HPGDNPC1KMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29217433 | 0.77 | XDH (0.68) | — | |
| SCHEMBL3403000 | 0.76 | NPC1 (0.50) | HPGDNPC1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215624-A1 | NOVEL 2-ARYLTHIAZOLE DERIVATIVE OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | (주)헥사파마텍 (KR) | 2021-10-28 | — | — | WO | disclosed |