Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244326 | 0.83 | CARM1 (0.32) | CARM1PRMT1 | |
| SCHEMBL23876031 | 0.81 | — | — | |
| SCHEMBL26420956 | 0.80 | CARM1 (0.31) | CARM1PRMT1 | |
| SCHEMBL23957363 | 0.76 | OPRM1 (0.33) | OPRM1OPRL1KDM1A | |
| SCHEMBL13358848 | 0.75 | — | — | |
| Methyl Alcohol SCHEMBL27917450 | 0.75 | ALDH1A1 (0.33) | CARM1PRMT1 | |
| SCHEMBL25165562 | 0.72 | — | — | |
| SCHEMBL12589089 | 0.71 | — | — | |
| SCHEMBL10147441 | 0.71 | — | — | |
| SCHEMBL26028300 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216770-A1 | SUBSTITUTED TETRAHYDROQUINAZOLINE COMPOUNDS AS KRAS INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2021-10-28 | — | — | WO | disclosed |