Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22327386 | 0.92 | NR1H4 (0.41) | NR1H4MAPTGAAKAT6AKMT2A | |
| SCHEMBL25571178 | 0.90 | KMT2A (0.44) | MAPTGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL24346424 | 0.88 | ALDH1A1 (0.47) | MAPTGAAKMT2AALDH1A1USP2 | |
| SCHEMBL21307969 | 0.85 | SMN1; SMN2 (0.37) | NR1H4MAPTGAAKMT2AALDH1A1 | |
| SCHEMBL22327196 | 0.85 | ALDH1A1 (0.36) | NR1H4MAPTGAAKMT2AALDH1A1 | |
| SCHEMBL26010471 | 0.85 | ALDH1A1 (0.37) | MAPTGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL22327368 | 0.85 | GAA (0.43) | NR1H4MAPTGAAKMT2AALDH1A1 | |
| SCHEMBL23957822 | 0.84 | GAA (0.43) | NR1H4MAPTGAAKAT6AKMT2A | |
| SCHEMBL25754063 | 0.83 | PRMT5 (0.37) | MAPTGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL21538137 | 0.83 | KMT2A (0.39) | NR1H4MAPTGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216998-A1 | MODIFIED NUCLEOTIDES AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2021-10-28 | — | — | WO | disclosed |