Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753752 | 0.93 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL26167764 | 0.92 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL26010471 | 0.92 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL25753972 | 0.91 | GAA (0.37) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL26167941 | 0.91 | MAOB (0.41) | ALDH1A1SMN1; SMN2KMT2AMAOBMEN1 | |
| SCHEMBL24346424 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL25571178 | 0.89 | KMT2A (0.44) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL21575546 | 0.87 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL21307969 | 0.86 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL23106220 | 0.86 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738072-B1 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738072-B1 | Nucleotide analogues | NUDT1, POLN, TYMP | ALDH1A1 1629/4885SMN1; SMN2 1337/4885GAA 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.