Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110971 | 0.92 | POLB (0.46) | POLBPIK3CDPDE5AKMT2ARAD52 | |
| SCHEMBL23958121 | 0.92 | ALOX12 (0.43) | CA12CA1CA2CA9PDE5A | |
| SCHEMBL29738614 | 0.87 | PIK3CD (0.46) | POLBPIK3CDPDE5AKMT2ARAD52 | |
| SCHEMBL23958265 | 0.87 | PIK3CD (0.46) | POLBPIK3CDPDE5AKMT2ARAD52 | |
| SCHEMBL30103265 | 0.86 | POLB (0.50) | POLBPIK3CDMAPT | |
| SCHEMBL24110913 | 0.86 | POLB (0.50) | POLBPIK3CDMAPT | |
| SCHEMBL24111022 | 0.86 | PIK3CD (0.42) | POLBPIK3CD | |
| SCHEMBL23958245 | 0.85 | PIK3CD (0.50) | PIK3CDKMT2ARAD52 | |
| SCHEMBL30103245 | 0.85 | PIK3CD (0.50) | PIK3CDKMT2ARAD52 | |
| SCHEMBL24110807 | 0.83 | PIK3CD (0.45) | PIK3CDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215537-A1 | 2-HETEROARYLAMINOQUINAZOLINONE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2021-10-28 | — | — | WO | disclosed |