Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958142 | 0.92 | POLB (0.42) | RAD52KMT2ACA12CA1CA2 | |
| SCHEMBL30103264 | 0.87 | MDM2 (0.49) | ALOX12RAD52KMT2AMAPTMDM2 | |
| SCHEMBL29738614 | 0.87 | PIK3CD (0.46) | ALOX12RAD52KMT2APDE7APDE5A | |
| SCHEMBL30025728 | 0.87 | TUBB4A (0.45) | ALOX12RAD52KMT2A | |
| SCHEMBL23958215 | 0.87 | MDM2 (0.49) | ALOX12RAD52KMT2AMAPTMDM2 | |
| SCHEMBL24110981 | 0.87 | ALOX12 (0.43) | ALOX12RAD52KMT2APDE7AMAPT | |
| SCHEMBL23958265 | 0.87 | PIK3CD (0.46) | ALOX12RAD52KMT2APDE7APDE5A | |
| SCHEMBL23958278 | 0.87 | TUBB4A (0.45) | ALOX12RAD52KMT2A | |
| SCHEMBL24110995 | 0.86 | ALOX12 (0.57) | ALOX12RAD52KMT2APDE7AMAPT | |
| SCHEMBL24110973 | 0.85 | ALOX12 (0.47) | ALOX12RAD52KMT2APDE7AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215537-A1 | 2-HETEROARYLAMINOQUINAZOLINONE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2021-10-28 | — | — | WO | disclosed |