Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 3/20 | 0.35 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958164 | 0.80 | TDO2 (0.38) | TDO2IDO2IDO1POLBTRPV4 | |
| SCHEMBL24110952 | 0.80 | TDO2 (0.43) | TDO2IDO2IDO1POLB | |
| SCHEMBL23958195 | 0.76 | ABL1 (0.35) | TDO2IDO2IDO1POLB | |
| SCHEMBL22237931 | 0.71 | TDO2 (0.39) | TDO2IDO2IDO1POLBTRPV4 | |
| SCHEMBL23958206 | 0.70 | ABCG2 (0.33) | IDO1 | |
| SCHEMBL29623155 | 0.66 | TDO2 (0.50) | TDO2IDO2IDO1POLB | |
| SCHEMBL23045334 | 0.66 | TDO2 (0.50) | TDO2IDO2IDO1POLB | |
| SCHEMBL23064665 | 0.64 | TDO2 (0.45) | TDO2IDO2IDO1POLB | |
| SCHEMBL23958242 | 0.64 | TDO2 (0.45) | TDO2IDO2IDO1POLB | |
| SCHEMBL30025705 | 0.64 | TDO2 (0.45) | TDO2IDO2IDO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215537-A1 | 2-HETEROARYLAMINOQUINAZOLINONE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2021-10-28 | — | — | WO | disclosed |