Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 3/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110803 | 0.80 | ALOX12 (0.40) | ABCG2L3MBTL1RAB9A | |
| SCHEMBL23958222 | 0.75 | KIT (0.35) | KDM4ENPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL23958164 | 0.71 | TDO2 (0.38) | IDO1 | |
| SCHEMBL23958151 | 0.70 | TDO2 (0.35) | IDO1 | |
| SCHEMBL23958216 | 0.69 | ALOX12 (0.44) | — | |
| SCHEMBL23958331 | 0.68 | LOXL3 (0.47) | ABCG2RAB9AIDO1 | |
| SCHEMBL23958265 | 0.67 | PIK3CD (0.46) | ABCG2IDO1 | |
| SCHEMBL23958245 | 0.67 | PIK3CD (0.50) | RAB9AIDO1 | |
| SCHEMBL24110971 | 0.67 | POLB (0.46) | ABCG2IDO1 | |
| SCHEMBL30103245 | 0.67 | PIK3CD (0.50) | RAB9AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215537-A1 | 2-HETEROARYLAMINOQUINAZOLINONE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2021-10-28 | — | — | WO | disclosed |