Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110803 | 0.88 | ALOX12 (0.40) | ALOX12MDM2CYP1A2POLBCYP3A4 | |
| SCHEMBL23958331 | 0.87 | LOXL3 (0.47) | ALOX12MDM2MAPTRAD52KMT2A | |
| SCHEMBL23958215 | 0.85 | MDM2 (0.49) | ALOX12MDM2PSDPOLBMAPT | |
| SCHEMBL30103264 | 0.85 | MDM2 (0.49) | ALOX12MDM2PSDPOLBMAPT | |
| SCHEMBL23958124 | 0.82 | MDM2 (0.51) | ALOX12MDM2PSDMAPTG6PD | |
| SCHEMBL23958227 | 0.81 | ALOX12 (0.46) | ALOX12MDM2PSDCYP1A2CYP3A4 | |
| SCHEMBL24111020 | 0.81 | ALOX12 (0.46) | ALOX12MDM2PSDCYP1A2CYP3A4 | |
| SCHEMBL24110995 | 0.79 | ALOX12 (0.57) | ALOX12MDM2PSDMAPTRAD52 | |
| SCHEMBL24110973 | 0.78 | ALOX12 (0.47) | ALOX12MDM2PSDMAPTRAD52 | |
| SCHEMBL23958356 | 0.78 | ALOX12 (0.48) | ALOX12MDM2PSDMAPTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215537-A1 | 2-HETEROARYLAMINOQUINAZOLINONE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2021-10-28 | — | — | WO | disclosed |