LOXL3

Lysyl oxidase homolog 3 · P58215 · LOXL3 on Sugi Atlas →

4,548 patent compounds predicted against LOXL3, 3,152 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL2642587	0.50	3/20
SCHEMBL1961156	0.47	3/20
Hydrochloric Acid (SCHEMBL4770707)	0.44	3/20
SCHEMBL445278	0.36	3/20
Thiram (SCHEMBL21144)	1.00	2/20
Disulfiram (SCHEMBL27213)	1.00	2/20
Thiram (SCHEMBL1216571)	1.00	2/20
Disulfiram (SCHEMBL4654748)	1.00	2/20
Disulfiram (SCHEMBL5364281)	0.94	2/20
Disulfiram (SCHEMBL5961375)	0.94	2/20
Thiram (SCHEMBL80195)	0.93	2/20
Thiram (SCHEMBL223860)	0.93	2/20
Thiram (SCHEMBL234787)	0.93	2/20
Thiram (SCHEMBL2773352)	0.93	2/20
Thiram (SCHEMBL2773357)	0.93	2/20
Thiram (SCHEMBL3741643)	0.93	2/20
Thiram (SCHEMBL3919769)	0.93	2/20
Disulfiram (SCHEMBL4734237)	0.89	2/20
Thiram (SCHEMBL1246182)	0.87	2/20
Thiram (SCHEMBL5078490)	0.87	2/20

Clinical trials — most relevant to LOXL3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD	PHASE4	RECRUITING
Endometriosis and Microvascular Dysfunction: Role of Inflammation	EARLY_PHASE1	RECRUITING
A Non-Interventional Pilot Study Assessing Whether Lysyl Oxidase-like 2 (LOXL2) is Present in Subjects With Scleroderma	nan	COMPLETED
In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme	nan	NOT_YET_RECRUITING
Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects)	nan	UNKNOWN
The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.	nan	ENROLLING_BY_INVITATION
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
Study of the Effect of Innate on the Inflammatory Response to Endotoxin	nan	RECRUITING
Gene Expression in Chronic Venous Leg Ulcers	nan	UNKNOWN
Increased Inflammation-resolving Activity by Omega-3 Monoglycerides in Peripheral Blood Mononuclear Cells (PBMC).	nan	RECRUITING
Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)	nan	COMPLETED
LobularCard Trial: Searching for Novel Germline Mutations in Lobular Breast Cancer Patients	nan	ACTIVE_NOT_RECRUITING
Genetical Background of Non-alcoholic Fatty Liver Disease (NAFLD) in Diabetes Mellitus and in Chronic Kidney Disease	nan	UNKNOWN
Developing a Management Approach for Patients With Late-Onset Pompe Disease	nan	ACTIVE_NOT_RECRUITING
Investigations of Juvenile Neuronal Ceroid Lipofuscinosis	nan	RECRUITING
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States	nan	COMPLETED
Inflammatory Genomics in Human Carotid Artery Disease	nan	COMPLETED
Linkage Study in Familial Pulmonary Fibrosis	nan	COMPLETED
Biomarkers of Lichen Sclerosus	nan	UNKNOWN
Identification of a New Gene Involved in Hereditary Lipodystrophy	nan	COMPLETED
Stone Disease in Children and Their Families	nan	COMPLETED
Chronic Obstructive Pulmonary Disease Gene Localization	nan	COMPLETED
Molecular Mechanisms of Fibrillin/LTBP Superfamily in Renal Fibrosis and Cardiorenal Syndrome	nan	UNKNOWN
Gene First Approach to Connective Tissue Disease	nan	COMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA)	nan	COMPLETED
Natural History and Outcomes in X-Linked Hypohidrotic Ectodermal Dysplasia	nan	COMPLETED
Role of Metabolic Enzymes in Non-Melanoma Skin Cancer	nan	COMPLETED
Genetic Variations That Increase the Risk for Calcium Kidney Stones: a Family-based Study	nan	COMPLETED
Chronic Kidney Disease : Role of Biological Factors and Apolipoprotein L1 Encoding Gene (APOL1)	nan	COMPLETED
Genetic Study of Age-Related Macular Degeneration	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a LOXL3 binder may also engage these)

Protein	Name	Similarity
Q9Z175	—	1.000	Q9Z175 →
Q924C6	—	1.000	Q924C6 →
Q8MJ24	—	1.000	Q8MJ24 →
B4F6N6	—	0.999	B4F6N6 →
LOXL4	Lysyl oxidase homolog 4	0.999	landscape →
F1RD85	—	0.998	F1RD85 →
A6H737	—	0.996	A6H737 →
Q5G265	—	0.996	Q5G265 →
Q5RFQ6	—	0.996	Q5RFQ6 →
Q08B63	—	0.995	Q08B63 →
LOXL2	Lysyl oxidase homolog 2	0.995	landscape →
B8A4W9	—	0.995	B8A4W9 →
Q5G266	—	0.994	Q5G266 →
E1C3U7	—	0.993	E1C3U7 →
Q5G270	—	0.993	Q5G270 →
O08762	—	0.992	O08762 →
Q5G268	—	0.992	Q5G268 →
PRSS12	Neurotrypsin	0.992	landscape →
Q5G269	—	0.992	Q5G269 →
P58022	—	0.992	P58022 →
Q5G271	—	0.991	Q5G271 →
Q5G267	—	0.991	Q5G267 →
A1L1V4	—	0.990	A1L1V4 →
B5DF27	—	0.990	B5DF27 →
Q2VL90	—	0.990	Q2VL90 →
Q9DBX3	—	0.989	Q9DBX3 →
Q9R097	—	0.989	Q9R097 →
Q3U435	—	0.989	Q3U435 →
Q92729	—	0.989	Q92729 →
G3V801	—	0.988	G3V801 →