Bromide

Bromide

SCHEMBL2395832

C=C[n+]1ccn(CCCCCCCCCCCCCC)c1.[Br-]

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.60
HSP90AA1 P07900 2/20 0.60
KMT2A Q03164 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
APAF1 O14727 1/20 0.60
NPC1 O15118 1/20 0.60
PLA2G1B P04054 1/20 0.60
MAPT P10636 1/20 0.60
MAPK1 P28482 1/20 0.60
HTT P42858 1/20 0.60
RAB9A P51151 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
ATG4B Q9Y4P1 1/20 0.60
FDPS P14324 17/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL2395819 1.00 MEN1 (0.60) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bromide SCHEMBL2396034 1.00 MEN1 (0.60) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bromide SCHEMBL2395867 1.00 MEN1 (0.60) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bromide SCHEMBL2399324 1.00 MEN1 (0.60) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bromide SCHEMBL2395677 1.00 MEN1 (0.60) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bromide SCHEMBL2395709 1.00 MEN1 (0.60) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL16307692 0.98 MEN1 (0.57) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL31501079 0.98 MEN1 (0.57) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL27921181 0.98 MEN1 (0.57) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL8450143 0.98 MEN1 (0.57) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284201-A1 EMULSION, EMULSION GEL ELECTROLYTE, AEROGEL, PREPARATION METHOD THEREFOR, AND USE THEREOF 山东大学 2023-01-19 WO claimed
WO-2023284201-A1 EMULSION, EMULSION GEL ELECTROLYTE, AEROGEL, PREPARATION METHOD THEREFOR, AND USE THEREOF 山东大学 2023-01-19 WO disclosed
US-9837181-B2 Processes for nanoparticle dispersions with ionic liquid-based stabilizers EASTERN MICHIGAN UNIVERSITY (US) 2017-12-05 US disclosed
US-20150086721-A1 PROCESSES FOR NANOPARTICLE DISPERSIONS WITH IONIC LIQUID-BASED STABILIZERS EASTERN MICHIGAN UNIVERSITY 2015-03-26 US disclosed
US-8920682-B2 Nanoparticle dispersions with ionic liquid-based stabilizers EASTERN MICHIGAN UNIVERSITY (US) 2014-12-30 US disclosed
US-20110233458-A1 Nanoparticle dispersions with ionic liquid-based stabilizers EASTERN MICHIGAN UNIVERSITY Office of Research Development (US) 2011-09-29 US disclosed