Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | FDPS | P14324 | 17/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2395832 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2396034 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395867 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2399324 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395677 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395709 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL16307692 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL31501079 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL27921181 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL8450143 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111811702-A | High-recovery conductive film pressure sensor and preparation method thereof | 无锡康森斯克电子科技有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-110975939-A | Ethylene carbonate hydrogenation heterogeneous catalyst, and preparation method and application thereof | 华东师范大学 | 2020-04-10 | — | — | CN | claimed |
| US-20250135435-A1 | SYSTEM FOR BATCH SCALE PRODUCTION OF EXTRACTION SORBENTS WITH 3D PRINTING AND ASSOCIATED METHOD OF USE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2025-05-01 | — | — | US | disclosed |
| CN-115894973-A | Preparation method of novel dual-network self-healing hydrogel sensor | 南京林业大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-114891167-A | Binary ionic liquid covalent bonding immobilized silicon-based material and preparation and application thereof | 武汉理工大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-109503780-B | Antibacterial hydrogel material and preparation method and application thereof | 大连医诺生物股份有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-108689838-B | Method for preparing formic ether by catalyzing esterification of formic acid and olefin through swellable acidic polyion liquid | 华东师范大学 | 2021-05-25 | — | — | CN | disclosed |
| CN-108579807-B | Cross-linked polymerization acidic ionic liquid alkylation catalyst and preparation method thereof | 江苏棋成化工有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-108929344-B | Method for separating phospholipid monomers in phospholipid homologues through polyion liquid | 浙江大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-111811702-A | High-recovery conductive film pressure sensor and preparation method thereof | 无锡康森斯克电子科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-110975939-A | Ethylene carbonate hydrogenation heterogeneous catalyst, and preparation method and application thereof | 华东师范大学 | 2020-04-10 | — | — | CN | disclosed |
| US-9837181-B2 | Processes for nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY (US) | 2017-12-05 | — | — | US | disclosed |
| US-9017716-B2 | Ophthalmic lens | MENICON CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20150086721-A1 | PROCESSES FOR NANOPARTICLE DISPERSIONS WITH IONIC LIQUID-BASED STABILIZERS | EASTERN MICHIGAN UNIVERSITY | 2015-03-26 | — | — | US | disclosed |
| US-8920682-B2 | Nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY (US) | 2014-12-30 | — | — | US | disclosed |
| US-20120148519-A1 | OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
| EP-2453293-A1 | OPHTHALMIC LENS | Menicon Co., Ltd. (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-20110233458-A1 | Nanoparticle dispersions with ionic liquid-based stabilizers | EASTERN MICHIGAN UNIVERSITY Office of Research Development (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148519-A1 | OPHTHALMIC LENS | AQP4, CRYAA, UACA | MEN1 2152/4885HSP90AA1 959/4885KMT2A 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.